Team

IMVACC core team

Prof. Fabio Candotti

 

After training in Medicine, Pediatrics, and Pediatric Allergy and Immunology at the Italian Universities of Brescia and Pavia, Prof. Candotti was granted a NIH Postdoctoral Fellowship in the laboratory of Dr. Michael Blaese at NCI and NHGRI before joining the Department of Pediatrics of the University of Brescia as an Assistant Professor in 1996 and eventually accepting a position at NHGRI that led to tenure at that institution in 2004. Ten years later, Prof. Candotti moved back to Europe to join the Division of Immunology and Allergy of the university Hospital of Lausanne in Switzerland, where he is Associate Professor of Medicine and Director of the Vaccine and Immunotherapy Center.
Throughout his career, Prof. Candotti focused on the study of the molecular basis of disorders of the immune system and the development gene therapy strategies for this heterogeneous group of diseases. He contributed to the discovery of JAK3-deficiency and AK2-deficiency as causes of SCID and performed extensive pre-clinical studies in the murine model supporting the feasibility of gene therapy for X-linked SCID and the Wiskott-Aldrich syndrome. From 2001 until 2014, Prof. Candotti co-led a series of gene therapy clinical trials for ADA-deficient SCID patients that studied the efficacy of different retroviral gene transfer vectors in humans.
Prof. Candotti has authored more than 110 peer-reviewed publications and numerous reviews and book chapters in the fields of immunodeficiency and gene therapy and is currently a member of the Editorial Board of the Journal of Clinical Immunology.

  e-mail: fabio.candotti@chuv.ch

Prof. I. Knezevic

  • Professors, Teachers, Professionals experts

Dr Ivana Knezevic is Scientist in Technologies, Standards and Norms Team, and Group Lead of Norms and Standards for Biologicals in the Department of Essential Medicines and Health Products (EMP) in the World Health Organization (WHO), Switzerland.

Dr Ivana Knezevic has 22 years of professional experience in standardization, scientific and regulatory overview of biologicals. She joined WHO Biological Standardization Programme in September 2000. Since 2006, she has been leading the team for standardization of vaccines and some biological therapeutics in WHO Headquarters. Main aspects of the work include development and establishment of WHO International Standards as well as the assistance to regulators, manufacturers and other users of these standards.

In the area of biotherapeutics, she coordinated the development of WHO’s Guidelines on evaluation of Similar Biotherapeutic Products (SBPs), and organized a series of workshops to facilitate the implementation of guiding principles for evaluation of biotherapeutic products into regulatory and manufacturers’ practices.

Prof. J.-P. Kraehenbuhl

Jean-Pierre Kraehenbuhl, MD, is the Chief Executive Officer of the Health Sciences eTraining (HSeT) Foundation. He is emeritus Professor at the University of Lausanne and Consultant at the Division of Immunology & Allergy of the University Hospital (CHUV), Lausanne, Switzerland. His field of expertise is mucosal immunology and vaccinology. He is a member of EMBO and the scientific co-founder of Oravax, now Acambis Ltd.
Jean-Pierre Kraehenbuhl received an M.D. from the University of Lausanne, Switzerland in 1967 and a PhD in 1973. He completed a postdoctoral fellowship with George Palade at the Rockefeller University and subsequently became an assistant professor at Yale University School of Medicine. In 1975, he returned to the Institute of Biochemistry at the University of Lausanne, where he became a full professor in 1984. He joined the Swiss Institute of Cancer Research (ISREC) as a senior staff member, working on epithelial-cell membrane trafficking, mucosal immunity and mucosal vaccine design.

Prof. Yannick Muller

Swiss Federal Medical Diploma, Faculty of Medicine, University of Geneva, 2007
MD-PhD,  Potential of T regulatory cells to protect pancreatic islet grafts, University of Geneva, 2007-2011.
Residency in internal medicine, University Hospital of Geneva, 2011-2014. Residency in immunology and allergy 2014-2016, Residency in transplantation, University Hospital of Lausanne 2016-2017

Postdoctoral fellowship on cell therapies engineering, University California, San Francisco (UCSF) 2017- 2020

Senior attending physician in immunology and allergy, University Hospital of Lausanne,  2020-ongoing
Assistant Professor, tenure track, Faculty of Biology and Medicine, University of Lausanne,  2021-ongoing

Prof. Laurent Perez

Short CV

2003: PhD–Biochemistry at European Molecular Biology Laboratory. Heidelberg, Germany.

2004-2006: Post-Doc–Biophysics at European Molecular Biology Laboratory. Heidelberg. Germany.

2006-2010: Research scientist at Novartis Institutes for BioMedical Research. United Kingdom.

2011-2020: Principal investigator. Institutes for Research Biomedicine. Switzerland.

2020-to date: Professor (associate), Faculty of Biology and Medicine, University of Lausanne. Switzerland

 

HSeT core team

Pascale Anderle

Pascale Anderle graduated in pharmacy from the Swiss Federal Institute of Technology Zurich (ETHZ). After gaining a PhD degree in life science from the ETHZ she then worked for a year at Covance CLS, Geneva in the field of clinical trials. Later, she moved to the USA for a postdoc experience in the lab of Wolfgang Sadee at UCSF San Francisco and OSU, Ohio concentrating on absorption and genomics in the intestine. Afterwards, she joined the groups of Jean-Pierre Kraehenbuhl and Michel Aguet as postdoc fellow at the Swiss Institute for Experimental Cancer Research (ISREC), partially in collaboration with the Nestle Research Center (NRC). The focus of her studies were on mucosal intestinal immunity and colon cancer and the use of genomics and in silico analysis. Being granted an EU project she moved to Istituto Oncologico della Svizzera Italiana (IOSI, Bellinzona) as junior group leader and then upon being invited to join a NCCR project to the University of Bern. During this period she was granted a CAS in applied statistics.
She is now a project coordinator for statistics and translational medicine. She participates in teaching activities at the University of Lausanne and ETHZ.

  e-mail: pascale.anderle@hset.org
  Phone: +41 79 6276 278

  Address: Health Sciences eTraining (HSeT) Foundation
Ch. des Boveresses 155
CH – 1066 Epalinges
CH – Switzerland

 

 

Jean-Pierre Kraehenbuhl

Health Sciences eTraining (HSeT) Foundation, CH 1066 Epalinges – Switzerland

BIO:

Jean-Pierre Kraehenbuhl, MD, is the Chief Executive Officer of the Health Sciences eTraining (HSeT) Foundation. He is emeritus Professor at the University of Lausanne and Consultant at the Division of Immunology & Allergy of the University Hospital (CHUV), Lausanne, Switzerland. His field of expertise is mucosal immunology and vaccinology. He is a member of EMBO and the scientific co-founder of Oravax, now Acambis Ltd.
Jean-Pierre Kraehenbuhl received an M.D. from the University of Lausanne, Switzerland in 1967 and a PhD in 1973. He completed a postdoctoral fellowship with George Palade at the Rockefeller University and subsequently became an assistant professor at Yale University School of Medicine. In 1975, he returned to the Institute of Biochemistry at the University of Lausanne, where he became a full professor in 1984. He joined the Swiss Institute of Cancer Research (ISREC) as a senior staff member, working on epithelial-cell membrane trafficking, mucosal immunity and mucosal vaccine design.

 

  e-mail: jean-pierre.kraehenbuhl@hset.org

  Phone: +41 21 692 58 56
  Fax:  +41 21 692 57 15

  Address: Health Sciences eTraining (HSeT) Foundation
Ch. des Boveresses 155
CH – 1066 Epalinges
CH – Switzerland

Alain Meystre

Health Sciences eTraining (HSeT) Foundation, CH 1066 Epalinges – Switzerland

BIO:

Alain was trained as a silk screener.
He worked in companies as industrial designer.
In 2005 he joined the HSeT eLearning team as a Animation Designer in charge of 2D and 3D animations.

  e-mail: alain.meystre@hset.org

  Phone: 021 692 57 74

  Address: Health Sciences eTraining (HSeT) Foundation
Ch. des Boveresses 155
CH – 1066 Epalinges
CH – Switzerland

 

 

Nicolas Peyraud

Dr Nicolas Peyraud is a medical doctor, specialized in paediatric. He completed his M.D. degree from the Medical University of Geneva, Switzerland, followed by a specialization in pediatric (Switzerland). He developed an extensive experience in humanitarian pediatric medicine and vaccination by working since 2009 for Medecins sans Frontières (MSF), in the field and at headquarter level (Geneva, Paris and Sydney). He completed The ADVAC course in 2016, a master in vaccinology (2016-2018) in Lausanne University (IMVACC) and two Scholar courses (Vaccination coverage survey and Immunization monitoring academy) organized by WHO in 2018. He worked as an APW (January-June 2018) on “Microarray patches (MAP) product development for Measles containing vaccines” within the Initiative for Vaccine Research (IVR) in the Department of Immunizations, Vaccines and Biologics (IVB), World Health Organisation (WHO).

He has experience in various aspects of Immunization activities done by MSF Ministries of Healh (MoH) and WHO, in various countries, including reactive and preventive mass vaccination campaign, preventive vaccination in emergencies, and support to Routine immunization program. He has some particular interest regarding Pneumococcus conjugate vaccine, Ebola candidates’ vaccines, Measles MAP vaccines, Cholera vaccines and Rotavirus vaccines.

Walter Reith

PhD, Emeritus Professor, Pathology & Immunology, University of Geneva. Pres

ident of the HSeT Foundation

The laboratory of Walter Reith has a long-standing interest in molecular and cellular immunology. Major themes of past research have included the genetic control and biological functions of Major Histocompatibility Complex class II (MHCII) mediated antigen presentation in humans and mice in the context of health and disease.

Current topics focus on the molecular and cellular mechanisms that regulate gene expression in specialized antigen presenting cells (APCs) – including B cells, various dendritic cell (DC) subsets and thymic epithelial cells – and the functions of these APCs in adaptive immune responses, the physiological processes that mediate the establishment and maintenance of immunological self-tolerance, and the pathological mechanisms that underpin the breakdown of immunological self-tolerance during the course of autoimmune diseases.

Contact:
e-mail:      walter.reith@unige.ch
Phone:    +41 79 250 3539
Address:  Faculty of medicine
University of Geneva
1 rue Michel-Servet
CH-1211 Geneva
Switzerland