IMVACC core team

Fabio Candotti

 

After training in Medicine, Pediatrics, and Pediatric Allergy and Immunology at the Italian Universities of Brescia and Pavia, Prof. Candotti was granted a NIH Postdoctoral Fellowship in the laboratory of Dr. Michael Blaese at NCI and NHGRI before joining the Department of Pediatrics of the University of Brescia as an Assistant Professor in 1996 and eventually accepting a position at NHGRI that led to tenure at that institution in 2004. Ten years later, Prof. Candotti moved back to Europe to join the Division of Immunology and Allergy of the university Hospital of Lausanne in Switzerland, where he is Associate Professor of Medicine and Director of the Vaccine and Immunotherapy Center.
Throughout his career, Prof. Candotti focused on the study of the molecular basis of disorders of the immune system and the development gene therapy strategies for this heterogeneous group of diseases. He contributed to the discovery of JAK3-deficiency and AK2-deficiency as causes of SCID and performed extensive pre-clinical studies in the murine model supporting the feasibility of gene therapy for X-linked SCID and the Wiskott-Aldrich syndrome. From 2001 until 2014, Prof. Candotti co-led a series of gene therapy clinical trials for ADA-deficient SCID patients that studied the efficacy of different retroviral gene transfer vectors in humans.
Prof. Candotti has authored more than 110 peer-reviewed publications and numerous reviews and book chapters in the fields of immunodeficiency and gene therapy and is currently a member of the Editorial Board of the Journal of Clinical Immunology.

  e-mail: fabio.candotti@chuv.ch

  e-mail: fabio.candotti@chuv.ch

Cecilia Graziosi

Chef d’Unité de Recherche at the Laboratory of AIDS Immunopathogenesis, CHUV, Lausanne since 1996.

BIO:

Italian by birth, spent most of her life in US and Switzerland. Postdoctoral studies at Yale University, Biology Department. Visiting scientist at the National Institute of Allergy and Infectious Diseases (NIAID), NIH. Executive MBA in Management of Technology (MoT), under the joined sponsorship of EPFL and HEC – UNIL in Lausanne. Speaks fluent Italian, English, French, Spanish, has a basic grasp of German and is currently learning Mandarin Chinese (HSK2).

Specialties:

Research:
HIV env sequence analysis, gp120 glycosylation, V4 intra-host variability, HIV immune escape, HIV antisense protein.
Light microscopy, in situ hybridization, RNA in vitro transcription, DNA amplification, molecular cloning, sequencing, cell culture, recombinant DNA technologies, handling of infectious materials.

Management:
Business development, Strategic thinking and planning, Training, Mentoring.

Service of Immunology and Allergy, Lausanne University Hospital (CHUV) – Switzerland

  e-mail:cecilia.graziosi@chuv.ch

  Phone:+(41) (21) 314 1065

  Fax:+(41) (21) 314 1070

  Address:Service of Immunology and Allergy, Lausanne University Hospital (CHUV)
Laboratoire d’Immunopathologie du SIDA
Service d’Immunologie et Allergie
Department of Medicine-CHUV
CLE/C207
Chemin de Boveresses 155
CH-1066 Epalinges
CH – Switzerland

 

Claude Meric

Claude MERIC received a PhD in molecular virology from the University of Geneva (Switzerland) and was a post-doctoral fellow (researcher) at Columbia University (New York City, USA). Then he joined Institut Mérieux (currently Sanofi Pasteur) in Lyon (France), where he worked for 24 years in R&D, mainly as a leader of various vaccine development projects including the Japanese encephalitis vaccine IMOJEV<sup>&reg;</sup>. From 2013 to 2018, he was a scientific expert in vaccine development at the the Swiss Vaccine Research Institute (SVRI) and Service of Immunology and Allergyof the Lausanne University Hospital (CHUV) in Switzerland and worked for the development of the International Master in Vaccinology (IMVACC). He is now contributing to IMVACC as a free-lance consultant.

  e-mail: claude.meric@hset.org

  Phone: +41 (0) 79 556 04 49

 

Giuseppe Pantaleo

M.D., Professor of medicine, is Chief of the Division of Immunology and Allergy. He is also Chief of the Laboratory of AIDS Immunopathogenesis at the Centre Hospitalier Universitaire Vaudois (CHUV), University of Lausanne, Switzerland. During the past ten years, Professor Pantaleo’s research has been focused on the delineation of the immunopathogenesis of HIV infection. His research activities have been focused on human T cell cloning, human T cell phenotypic and functional analysis, T cell activation, differentiation and memory, immunopathogenesis of HIV infection, HIV distribution in different anatomic compartments, antiretroviral therapy, immune reconstitution after antiretroviral therapy, immune-based therapeutic strategies and vaccines.

Professor Pantaleo is author and co-author of about 270 publications in international scientific journals.

  e-mail: giuseppe.pantaleo@chuv.ch

Address: Service of Immunology and Allergy, Lausanne University Hospital (CHUV), Swiss Vaccine Research Institute (SVRI), University of Lausanne –  CH – Switzerland

 

Matthieu Perreau

Matthieu Perreau is a senior immunologist at the Department of Immunology and Allergy, Lausanne University Hospital, in Switzerland. He received his undergraduate degree at Nottingham Trent University in Microbiology and Biochemistry and then completed his Master’s in Haematology at the University of Denis Diderot in Paris. He subsequently joined Dr Eric Kremer’s laboratory at Montpellier II University, France, to obtain his PhD during which he focused on the interactions between viral vectors and the human immune system. In 2006, Dr Perreau joined Professor Giuseppe Pantaleo’s laboratory in Lausanne University Hospital, Switzerland, and investigated several projects in basic and applied immunology focusing on the evaluation of HIV-1 vaccine
immunogenicity and on the delineation of HIV-1 immunopathogenesis. His research has been acknowledged in several publications including Journal of Virology, Journal of Experimental Medicine and Nature Medicine

  e-mail: matthieu.perreau@chuv.ch

HSeT core team

Pascale Anderle

Pascale Anderle graduated in pharmacy from the Swiss Federal Institute of Technology Zurich (ETHZ). After gaining a PhD degree in life science from the ETHZ she then worked for a year at Covance CLS, Geneva in the field of clinical trials. Later, she moved to the USA for a postdoc experience in the lab of Wolfgang Sadee at UCSF San Francisco and OSU, Ohio concentrating on absorption and genomics in the intestine. Afterwards, she joined the groups of Jean-Pierre Kraehenbuhl and Michel Aguet as postdoc fellow at the Swiss Institute for Experimental Cancer Research (ISREC), partially in collaboration with the Nestle Research Center (NRC). The focus of her studies were on mucosal intestinal immunity and colon cancer and the use of genomics and in silico analysis. Being granted an EU project she moved to Istituto Oncologico della Svizzera Italiana (IOSI, Bellinzona) as junior group leader and then upon being invited to join a NCCR project to the University of Bern. During this period she was granted a CAS in applied statistics.
She is now a project coordinator for statistics and translational medicine. She participates in teaching activities at the University of Lausanne and ETHZ.

  e-mail: pascale.anderle@hset.org
  Phone: +41 79 6276 278

  Address: Health Sciences eTraining (HSeT) Foundation
Ch. des Boveresses 155
CH – 1066 Epalinges
CH – Switzerland

 

 

Nathalie Debard

Health Sciences eTraining (HSeT) Foundation – Switzerland

BIO:

Nathalie Debard received a PhD in immunology in 1996 from the University of Chatenay–Malabry (France) and completed a post-doctorate in the laboratory of Jean-Pierre Kraehenbuhl at the Swiss Institute for Experimental Cancer Research (ISREC; Epalinges, Switzerland) concentrating on M cell development in the intestine. She is now a project coordinator for immunology and nephrology in the HSeT foundation. She participates in teaching activities at the University of Lausanne.

  e-mail: nathalie.debard@hset.org

Phone: +41 21 692 58 69

  Address: Health Sciences eTraining (HSeT) Foundation
Ch. des Boveresses 155
CH – 1066 Epalinges
CH – Switzerland

Jean-Pierre Kraehenbuhl

Health Sciences eTraining (HSeT) Foundation, CH 1066 Epalinges – Switzerland

BIO:

Jean-Pierre Kraehenbuhl, MD, is the Chief Executive Officer of the Health Sciences eTraining (HSeT) Foundation. He is emeritus Professor at the University of Lausanne and Consultant at the Division of Immunology & Allergy of the University Hospital (CHUV), Lausanne, Switzerland. His field of expertise is mucosal immunology and vaccinology. He is a member of EMBO and the scientific co-founder of Oravax, now Acambis Ltd.
Jean-Pierre Kraehenbuhl received an M.D. from the University of Lausanne, Switzerland in 1967 and a PhD in 1973. He completed a postdoctoral fellowship with George Palade at the Rockefeller University and subsequently became an assistant professor at Yale University School of Medicine. In 1975, he returned to the Institute of Biochemistry at the University of Lausanne, where he became a full professor in 1984. He joined the Swiss Institute of Cancer Research (ISREC) as a senior staff member, working on epithelial-cell membrane trafficking, mucosal immunity and mucosal vaccine design.

 

  e-mail: jean-pierre.kraehenbuhl@hset.org

  Phone: +41 21 692 58 56
  Fax:  +41 21 692 57 15

  Address: Health Sciences eTraining (HSeT) Foundation
Ch. des Boveresses 155
CH – 1066 Epalinges
CH – Switzerland

Alain Meystre

Health Sciences eTraining (HSeT) Foundation, CH 1066 Epalinges – Switzerland

BIO:

Alain was trained as a silk screener.
He worked in companies as industrial designer.
In 2005 he joined the HSeT eLearning team as a Animation Designer in charge of 2D and 3D animations.

  e-mail: alain.meystre@hset.org

  Phone: 021 692 57 74

  Address: Health Sciences eTraining (HSeT) Foundation
Ch. des Boveresses 155
CH – 1066 Epalinges
CH – Switzerland

 

 

Michelle Rossier

Michelle Rossier received an M.D. from the University of Lausanne (Switzerland) and completed a MD thesis medical Department of Physiology of the University of Geneva. After a postdoctoral research fellowship, she held an assistant research physiologist position at the Department of Physiology, University of California, San Francisco. She then returned to the Institute of Pharmacology at the University of Lausanne, where she became a “maître assistant”. From 1977 to 2006 she was Director of the clinical laboratories of Hematology, Clinical Chemistry and Microbiology at the Hospital of Morges, Switzerland. In 2001 she held the same position with Viollier Inc., one of the largest private clinical laboratories in Switzerland. She joined the HSeT core team in February 2006 to become a project coordinator for several HSeT projects.

  e-mail: michelle.rossier@hset.org

  Phone: 0041 21 692 58 60

  Address: Health Sciences eTraining (HSeT) Foundation
Ch. des Boveresses 155
CH – 1066 Epalinges
CH – Switzerland